engine Protein Arrays
Your chance for breaking discoveries
Our high-density protein arrays present over 15,000 human proteins and peptides derived from different tissues. The corresponding cDNA expression libraries were validated, and advanced in more than 15 years of experience. The combination of established, published and well-characterized antigens and neoantigens enables you to discover novel biomarkers hypothesis-free and unbiased.
Unique coverage of human proteome
High content of >15,000 full-length antigens, protein isoforms & peptides, neoantigens & frameshift peptides.
Largest neoantigen library
Address questions or discuss results with your dedicated, experienced expert.
Robust & documented technology
- Published in >100 studies:
Proven by scientific community - Robust technology:
E. coli clones spotted in high density on PVDF membrane - Trusted origin:
based on the technique of RZPD, imaGenes and Source Biosciences - Clones in duplicate:
for reliable and reproducible results - Permanent evaluation of quality:
periodic review of the annotation
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Protein Arrays
hEXselect Protein Array
Human fetal brain cDNA library
>57,000 spots in total with >21,000 distinct human antigens representing >7,000 different genes.
1,100 € per array, bulk discount possible
UniPEx Protein Array
Human fetal brain, T‑cells, lung and colon cDNA library
>36,000 spots in total with >15,000 distinct human antigens representing >6,000 different genes.
1,100 € per array, bulk discount possible
Custom Protein Array
Customized
Generated from subsets of our human fetal brain, T‑cells, lung and colon cDNA library. Size ranges from 500 up to 13,000. Clones spotted in duplicates.
Prices on request.
Enzymatic modification
Investigate if citrullination, phosphorylation or carbamylation are disease-associated or causative. Our protein arrays can be modified enzymatically. For example, rheumatoid arthritis autoantibodies are usually directed against cyclic citrullinated peptides.
Citrullination
Phosphorylation
Carbamylation
Protein array research database
What our customers say
“To identify potential biomarkers associated with axial spondyloarthritis, we used the engine biomarker screening service. As a first step, we had the autoantibody profiles of 4 patients investigated. In the course of this investigation on UniPEx arrays, more than 50 potential antigens could be identified. A subarray was created for these candidates and in a second step, a larger number of patients could easily be testet. This allowed us, to further narrow down our potential biomarker candidates. These will now be validated in further studies on a different platform. The engine protein arrays are a great tool for broad biomarker screening in the field of autoimmune diseases. The engine team has supported us throughout the process and the screening service has allowed us to focus on our other projects in parallel with the testing.”
Torsten Witte, Prof. Dr. Med.
Natalie Fadle
Ole Pless, PHD
Bernhard Reuss, PHD
Şükrü Atakan
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