engine – the biomarker company

Pioneers with more than 15 years of experience.

We are your engine for your biomarker discovery! Let us boost your research with our engine human protein arrays.

Protein arrays are in our DNA

In 1998 K. Büssow et al. cloned and selected a human fetal brain cDNA library in E. coli (hEx1 library) in a collaboration between the Max Planck Institute (MPI) for Molecular Genetics and the Resource Center of the German Human Genome Project (RZPD). The clones were then spotted as high-density filters and the expressed proteins were detected by antibodies. This work has built the basis for the engine protein arrays. The hex1 arrays were further developed from 2007 onwards by the RZPD spin-off imaGenes GmbH (later Source BioScience) to the hEXselect Array. The cDNA library for the high-density protein arrays was extended by protein expression libraries from human CD4+ T-cells, lung, colon so the UniPEx Array was created.

Read more about: Supercharging biomarker discovery since RZPD

We are the legal successor of RZPD, imaGenes, Source Biosciences.

  • 1998: first publication about protein arrays by MPI for molecular genetics
  • 2000: products developed at RZPD (Ressourcenzentrum für Genomforschung)
  • 2007: marketed by the spin-off imaGenes GmbH (Berlin)
  • 2010: imaGenes taken over by Source BioScience (UK)
  • 2013: products discontinued
  • Technology and assets acquired by engine in 2016

Dedicated to protein arrays

Our products and services are made by scientists for scientists.

Prof. PhD Jörg-M. Hollidt
PhD in physical chemistry (TU, Berlin) and Professor of Business Administration for SMEs (UAS, Mittweida) with enthusiasm for the big picture.

PhD Ute Nonhoff
Head of Research & Development
PhD in Biology (FU, Berlin) with several years of experience in protein arrays and passionate about defending scientific correctness.

Juliane Metzke
Product Specialist

M. Sc. in Biochemistry (FU, Berlin) with passion for interactions with proteins and customers.

Ulrike Borau
Finance & Controlling
For many years, she has brought understanding to scientists and watched our processes like a hawk.

Moritz Schneider-Schwarzkopf
Development & Production

Has switched from Saccharomyces cerevisiae to Escherichia coli and found his friend and master in it. Dipl.-Ing. Biotechnology & Brewing Science (TU, Berlin).

Has come to us.

Our partners

Research is cooperation. Therefore we work intensively with our partners to offer our customers solutions in all areas.

In the Diagnostik Netzwerk Berlin-Brandenburg, companies and institutes have joined forces with users from clinics and medical laboratories to develop and market new and improved in vitro diagnostics that meet their needs.

in.vent Diagnostica GmbH is europe’s leading supplier of high-quality human biospecimen. Precise diagnostics and comprehensive tests are needed for early detection and classification of diseases and for monitoring. in.vent supplies the right samples for each in-vitro diagnostics project.

CANDOR Bioscience supplies solutions to immunodiagnostics kit manufacturers. Stabilizers, surface blockers and HAMA & interference blockers help to avoid false results and enable longer shelf lives for kits such as ELISA, lateral flow assays, protein arrays and others.

The AIT Austrian Institute of Technology is Austria’s largest research institute and regards itself as a highly specialised R&D partner for industry. One focus of the Unit Molecular Diagnostics is provide services with its innovative high throughput technologies, using protein and peptide microarrays, bead arrays, multiplex protein like pre-defined and customized analysis and assay development.

Contact us


Neuendorfstr. 17
16761 Hennigsdorf

Production Site

Robert-Rössle-Str. 10
Erwin-Negelein-Haus (D79)
13125 Berlin


Mrs. Juliane Metzke


+49 (0) 3302 551990

+49 (0) 163 7812775

Or simply send us your question via the following contact form:

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